Coltsfoot is considered unsafe for anyone, but people with the following conditions should be especially careful about avoiding this plant.
Special Precautions & Warnings:
Pregnancy and breast-feeding: Coltsfoot preparations containing hepatotoxic PAs might cause birth defects and liver damage. It is not known whether coltsfoot preparations that are free of these chemicals are safe to use during pregnancy. So, it is best to avoid using coltsfoot altogether if you are pregnant.
If you are breast-feeding, do not take coltsfoot either. Hepatotoxic PAs can get into breast milk. Even if the product is certified hepatotoxic PA-free, it is best to avoid use. Not enough is known about the safety of using hepatotoxic PA-free coltsfoot during breast-feeding.
Allergy to ragweed and related plants: Coltsfoot may cause an allergic reaction in people who are allergic to the Asteraceae/Compositae plant family. Members of this family include ragweed, chrysanthemums, marigolds, daisies, and many others. If you have allergies, be sure to check with your healthcare provider before taking coltsfoot.
High blood pressure, heart disease: There is a concern that coltsfoot taken in large amounts might interfere with treatment for these conditions. Do not use coltsfoot if you have these conditions.
Liver disease: There is a concern that hepatotoxic PAs might make liver disease worse. Do not use coltsfoot if you have this condition.